Making the list include Afriyie Acquah, Jordan Ayew, Andre Ayew and John Boye while skipper Asamoah Gyan has been relegated to the bench.
The match between the Black Stars and Wasps kicks off at the 30,000 capacity Stade Amahoro in the capital Kigali at exactly 1.30pm.
See the starting XI below:
Razak Braimah, Harrison Afful, Baba Rahman, Amartey, John Boye, Afriyie Acquah, Christian Atsu, Mubarak Wakaso, Richmond Boakye-Yiadom, Andre Ayew, Jordan Ayew.
On Tuesday, Ghana won in the friendly game against Congo in Brazzaville on 3 – 2 margin.